National Geographic The Incredible Human Body

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00:00:08 Narrator: The human body...
00:00:09 206 bones...650 muscles...
00:00:14 A heart that will beat
00:00:19 Lungs that deliver breath
00:00:25 All superbly orchestrated
00:00:28 And billions of miles
00:00:31 In combinations that
00:00:36 100 trillion cells,
00:00:43 Every day it takes us
00:00:46 Pushing the frontiers,
00:00:49 Defying the boundaries
00:00:56 A basketball star redefines
00:01:01 PJ Brown: I think
00:01:04 you'd probably see our heart
00:01:08 Narrator: A childless couple challenges
00:01:12 Mark Sauer:
00:01:14 a 50-50 chance
00:01:16 but you just don't know going
00:01:19 Narrator: A schoolteacher
00:01:21 that lurks deep
00:01:23 Frederick Meyer:
00:01:25 The tumor's gonna kill him.
00:01:28 Lisa Toenies:
00:01:30 because I didn't know what
00:01:36 Narrator: These are the
00:01:38 but they take place
00:01:41 in realms we could never see.
00:01:43 But now we can.
00:01:46 Today, awesome new technology
00:01:48 allows us to peer inside
00:01:52 to see a brain think,
00:02:00 to discover
00:02:02 of the incredible human body.
00:02:49 Donald Coffey:
00:02:52 It's mind-boggling to see
00:02:54 how the whole system
00:02:59 The heart beats. The brain
00:03:05 Your eyes are capable of
00:03:08 and storing the light,
00:03:13 If you approached me
00:03:15 and said, "make me a system"
00:03:16 "that can retrieve that kind
00:03:19 "Put it with memory, for
00:03:23 This is an amazing
00:03:26 And it can all be stored
00:03:29 which can all come together and form
00:03:34 with each one of them
00:03:41 Narrator:
00:03:43 a new human being begins
00:03:46 every quarter of a second
00:03:52 To understand the amazing
00:03:55 we must begin at the beginning,
00:04:05 For some couples,
00:04:07 that seemingly commonplace
00:04:13 Today, reproductive science -
00:04:17 to the magic of nature--
00:04:21 And here it will provide
00:04:24 into the beginning
00:04:26 Inez: My husband and I
00:04:30 and we...we were trying,
00:04:34 And it just dawned on us one day
00:04:37 that something
00:04:40 that I'm not getting pregnant,
00:04:44 Sauer: What I want to do
00:04:46 talking about in vitro
00:04:49 Narrator: Dr. Mark Sauer
00:04:52 but about once a week
00:04:54 will help to bring a baby
00:04:56 through in-vitro fertilization,
00:05:01 With dr. Sauer's help,
00:05:05 will have a 50-50 chance
00:05:09 IVF really is
00:05:12 even though
00:05:14 because it allows us
00:05:16 and create an embryo,
00:05:19 than what happens in nature.
00:05:22 Narrator: But unlike in nature, remarkable
00:05:26 will allow us to observe
00:05:30 in extraordinary detail.
00:05:33 Sauer: So we'll be seeing you
00:05:36 Inez: Okay. We're just
00:05:42 Woman: You can go ahead
00:05:44 and try it again maybe
00:05:47 Narrator: Inez begins a regime
00:05:49 that will stimulate her ovaries
00:05:51 to produce more than
00:05:55 Inez: Do it like this,
00:05:57 Woman: You'll wipe
00:05:59 ...wipe with alcohol.
00:06:00 Like so, okay?
00:06:04 A little bit faster than that...
00:06:06 Yeah, like that.
00:06:08 Oh my god...
00:06:12 Narrator: It's time.
00:06:14 As hoped, many eggs are ready.
00:06:27 As she is put to sleep,
00:06:31 [Inez speaks]
00:06:34 Man: What was that?
00:06:38 Woman: She said,
00:06:40 Man: That's what
00:06:41 Sauer: We'll start
00:06:44 There's a lot of follicles.
00:06:45 You can see the needle tip
00:06:53 is a single cell -
00:06:56 barely visible to the eye.
00:07:00 Coffey: Most people have
00:07:03 If I crudely scrape
00:07:06 I have about 10,000 cells
00:07:09 These things are really small!
00:07:11 You can't see that
00:07:14 and yet, that can make a human.
00:07:21 Narrator: One by one,
00:07:30 When the safety
00:07:32 Darryl's semen is collected.
00:07:37 will filter out
00:07:39 the dead and less-healthy sperm.
00:07:43 Prosser: Okay,
00:07:45 It has not been processed.
00:07:47 And so, from this
00:07:49 with the post-processing sample.
00:07:52 You can see that the sample
00:07:55 almost all of the sperm
00:07:59 And they look like
00:08:14 Narrator: Dr. Prosser positions
00:08:20 And readies the single sperm
00:08:22 from a pool of hundreds.
00:08:29 the sperm is injected
00:08:30 and the critical moment
00:08:57 Like a great celestial director,
00:09:02 guiding sperm to another egg.
00:09:10 If this is the meeting
00:09:13 we are observing -
00:09:16 the first miracle of many
00:09:18 that will lead to
00:09:25 At this moment,
00:09:29 as genetic material from Inez's
00:09:33 are shuffled together.
00:09:35 Each contributes
00:09:38 strands of information
00:09:43 Like a microscopic
00:09:45 each chromosome carries genes
00:09:50 the most basic design element
00:09:54 Together, these molecules
00:09:58 the blueprint for
00:10:04 The human body, like a house,
00:10:07 rolled-up set of blueprints,
00:10:09 which is rolled up
00:10:11 and it's a DNA sequence,
00:10:15 it says "female;"
00:10:18 it says "about five foot eight
00:10:22 Narrator: The epic accomplishment
00:10:26 the codebook of human life -
00:10:29 of biological revelations.
00:10:32 Craig Venter is at the crest
00:10:36 Venter: A genome is our collection
00:10:40 It's a four-letter alphabet
00:10:43 and when we sequence the genome,
00:10:46 of roughly three billion
00:10:52 It's elegant in it's simplicity.
00:10:55 The genetic code
00:10:58 we substitute A, C, G, and T
00:11:01 We attach
00:11:04 one color for each of
00:11:08 It's like just solving
00:11:10 only the jigsaw puzzle has, in
00:11:17 So it came in a very big box
00:11:19 and there was no picture
00:11:22 Narrator: Putting the pieces
00:11:25 has provided knowledge
00:11:26 that will enhance the quality
00:11:29 and perhaps even extend it.
00:11:35 Coffey: We're at the
00:11:38 in a very powerful force.
00:11:41 There's some relationship
00:11:45 So if we can control
00:11:47 will we be able
00:11:51 Well, it's distant stuff,
00:11:57 Knowing the human genome,
00:12:01 is a major step forward
00:12:04 the making of this wonderful
00:12:08 Through the history of time,
00:12:10 the DNA sequence
00:12:13 through generation after
00:12:17 and now it continues
00:12:29 Narrator: Overnight, DNA from Inez's eggs
00:12:35 and 13 of the 27 eggs
00:12:39 that indicates success.
00:12:44 With exquisite grace,
00:12:49 two become four; each duplicates
00:12:56 The enchanted progression
00:13:02 For five days,
00:13:05 Finally, the division
00:13:09 known as blastocysts,
00:13:11 and any one
00:13:13 may become a part
00:13:17 Prosser: This embryo here...
00:13:18 If you look at the outer shell
00:13:21 it's very thin.
00:13:23 The embryo is getting ready
00:13:27 It's a very nice blastocyst.
00:13:30 The inner cell mass is going
00:13:34 what you normally think of
00:13:37 Arms, head, legs, toes, fingers.
00:13:40 And, actually,
00:13:44 is where you find
00:13:47 which are very much in the
00:13:51 that's going on right now.
00:13:56 Narrator: Embryonic stem cells stand
00:14:02 These magical
00:14:05 will eventually transform into
00:14:10 This extraordinary potential
00:14:13 has made isolating them one
00:14:17 Although a controversial one.
00:14:21 Dr. John Gearhart is at the
00:14:26 Gearhart: These cells
00:14:29 One is that if you
00:14:32 under certain
00:14:34 they will continue to form
00:14:37 So you can grow a room full
00:14:39 and they are undifferentiated
00:14:44 If you take some
00:14:46 and you put them out
00:14:47 in different kinds
00:14:49 these cells are capable
00:14:52 that are present
00:15:05 that are beating as a tissue.
00:15:11 Narrator: Once these were stem cells
00:15:15 Dr. Gearhart has directed their
00:15:18 now able to beat
00:15:24 Gearhart: It's always been
00:15:27 that someday we'd be able
00:15:31 that were either damaged
00:15:36 But we really never had the
00:15:43 Now we have in the laboratory,
00:15:47 virtually all the cell types
00:15:49 that are present
00:15:53 Coffey: They make a "you."
00:15:58 That's pretty powerful!
00:16:00 And I can
00:16:02 And understand
00:16:04 Now we're set up to answer
00:16:06 one of the first
00:16:08 about how a human is made.
00:16:10 Sauer: As we hoped,
00:16:15 And ready-to-transfer
00:16:18 of growth in the lab,
00:16:21 Inez's embryos
00:16:24 She is shown what might turn out
00:16:28 Sauer: Now, with
00:16:30 if I put in three,
00:16:35 may be as high as 40
00:16:39 If that makes you overly nervous,
00:16:42 then I would suggest
00:16:44 which still gives you a very
00:16:49 What do you think
00:16:52 Ummmm... I think we'll
00:16:58 Okay. Okay.
00:17:03 Inez: At first, I was
00:17:05 I said, "Well, if one doesn't
00:17:09 And, you know, at the last minute
00:17:12 I said, "Well,
00:17:17 I mean, for the amount of things
00:17:19 to just do one was not
00:17:25 And then we started
00:17:27 "Wow, two's
00:17:31 So maybe...
00:17:33 Sauer: Now you wanna do...
00:17:34 Yeah, I'll do
00:17:37 I'll put in
00:17:39 Okay.
00:17:40 Bob, she wants
00:17:57 Narrator: The three embryos
00:18:01 and guided onto the lining
00:18:10 Sauer: There it goes...
00:18:15 Real well... This is what
00:18:19 I really think it's a 50-50
00:18:23 Whether or not
00:18:24 we'll find out in about 10 days.
00:18:27 Inez: I didn't get,
00:18:30 because they said, you know,
00:18:31 there is a chance
00:18:33 might not be successful,
00:18:35 to really get
00:18:37 so I just kept it like that.
00:18:40 Narrator:
00:18:43 but it will be
00:18:46 27 eggs collected...
00:18:51 Five viable blastocysts...
00:18:57 the chance to be a mother.
00:19:05 Scott: Does that look right?
00:19:08 Okay, what about
00:19:12 Narrator: Much of what we know about
00:19:15 emerges when it is
00:19:20 Scott Toenies, a veteran
00:19:23 and football coach
00:19:26 is the victim
00:19:28 that have led
00:19:30 of a massive brain tumor.
00:19:35 Two months ago, Scott's tumor
00:19:39 as did the frequency
00:19:42 Often he would pass out.
00:19:46 If left untreated, Scott may
00:19:52 Scott: I had
00:19:55 And all of a sudden,
00:19:58 "We need to do something."
00:20:02 Narrator:
00:20:04 travel to
00:20:08 where high-risk brain surgery
00:20:15 The brain is a greedy organ.
00:20:18 While Scott's brain makes up
00:20:22 it consumes 20 percent
00:20:26 Floating within his skull,
00:20:29 contain 100 billion cells
00:20:32 and the eager connections
00:20:34 bring consciousness.
00:20:37 But if these connections are
00:20:41 the brain misfires
00:20:42 and electrical storms
00:20:49 Witner: Mr. Toenies?
00:20:50 Yes.
00:20:51 My job here today
00:20:53 Okay.
00:20:55 Okay? And they create a reference
00:20:59 Narrator: Knowing the exact
00:21:02 One wrong move in any direction
00:21:06 remove crucial brain cells,
00:21:14 Witner: And you're all set.
00:21:26 Narrator: The MRI scan shows
00:21:30 But it is essential to identify
00:21:32 the specific functions
00:21:35 and to do so
00:21:39 From these scans,
00:21:41 a startling 3-D visualization
00:21:43 is prepared for his surgeons.
00:21:46 This will enable them
00:21:49 as if his skull and brain
00:21:54 when I first came to Mayo,
00:21:56 I was doing some imaging,
00:22:00 and was talking
00:22:02 and showed him
00:22:04 of the brain and the tumor.
00:22:06 And he told me something
00:22:09 if I can see it,
00:22:13 What you can see, is that
00:22:17 So if I want
00:22:19 and then I want
00:22:21 and I want to move down,
00:22:23 that will move me down to
00:22:27 It's a totally different picture.
00:22:30 It's the same as walking inside a building,
00:22:38 Narrator: Scott and Lisa
00:22:41 who will perform
00:22:45 Meyer:
00:22:47 that's infiltrated through
00:22:50 to the part of the brain
00:22:53 that controls movement
00:22:55 and it's very close
00:22:59 And it's sitting within an area
00:23:01 that helps initiate and coordinates
00:23:04 We can see it starting...
00:23:07 this is the left
00:23:08 This is all tumor here, and
00:23:14 Okay.
00:23:15 Meyer: ...and here, and here.
00:23:21 Narrator: The image grimly reveals
00:23:25 Scott's tumor is in a
00:23:29 in the cerebrum,
00:23:32 thought to be
00:23:35 The massive tumor lies between
00:23:38 the crucial regions controlling
00:23:41 and it is perilously intertwined
00:23:46 To avert damage to these areas,
00:23:48 the surgeons
00:23:50 to speak to Scott as they work
00:23:52 and that means
00:23:55 through most of the operation.
00:23:57 It is his best chance
00:24:01 Meyer: This is
00:24:04 I think it's
00:24:07 I mean, it's an awful decision
00:24:11 How serious is it?
00:24:13 If he doesn't have successful
00:24:17 whatever that treatment
00:24:20 the tumor's going to kill him.
00:24:23 And he's a young man,
00:24:27 Lisa: Those words just hit me
00:24:31 The things that ran through
00:24:34 my family - and...is this gonna
00:24:41 Narrator:
00:24:43 and the big moment
00:24:45 as she awaits the results
00:24:51 I just want to let you know
00:24:53 that your pregnancy test
00:24:57 ...which is wonderful.
00:25:00 Inez: Thank you.
00:25:02 Well, give me a hug!
00:25:05 Inez: Yes, I was surprised. Yeah
00:25:10 Nobody looked sad or anything
00:25:14 And I said,
00:25:17 So that kind of
00:25:18 Everybody was like, you know,
00:25:21 Too normal for me, you know,
00:25:24 "I guess everything
00:25:26 Inez: Hello?
00:25:29 Mm... Hmm. Well, I got good news
00:25:35 Why are you laughing?
00:25:38 He said, "You're pregnant?
00:25:47 Sauer:
00:25:49 because now we have
00:25:51 It's real, it's a pregnancy,
00:25:52 That's what
00:25:54 Watching this embryo
00:25:58 and the fetus
00:26:00 is really the fun part
00:26:07 Thorton: Now the first thing
00:26:09 is that right here
00:26:11 Inez: Okay.
00:26:13 Thorton: Okay? And you see the little
00:26:15 That's the heartbeat
00:26:17 Inez: Can I get
00:26:18 Thorton: I'm gonna give you
00:26:21 Now, you have some...
00:26:24 You actually have two...
00:26:27 There's one baby there, okay?
00:26:30 And then you see
00:26:33 Let me get a nice view.
00:26:36 Right there, you can see
00:26:38 See that? By the "x"?
00:26:42 I hope that's good news.
00:26:44 Yeah!
00:26:46 Inez: That was my first time
00:26:49 So...that was, like, pretty
00:26:57 You look at that
00:26:59 It's a living baby growing
00:27:04 That's when it
00:27:07 This is the
00:27:12 Gearhart:
00:27:14 where all of a sudden the
00:27:17 is the circulatory system.
00:27:19 You see
00:27:20 The heart is in there beginning
00:27:23 and it's very critical, because
00:27:28 Without it's own
00:27:31 Narrator: At 22 days,
00:27:34 no bigger than a poppy seed -
00:27:39 Soon the embryo
00:27:42 through the umbilical cord
00:27:44 for a fresh supply
00:27:48 Now just a simple tube,
00:27:51 this heart will grow into
00:27:54 able to beat
00:27:59 In a 70-year lifespan,
00:28:01 the human heart will beat
00:28:04 which may explain why yogis like
00:28:08 but in heartbeats.
00:28:19 NBA players count the minutes
00:28:22 And on this night, the aerobic
00:28:25 are being put to severe test.
00:28:29 They are competing in
00:28:31 what will be the longest game
00:28:33 a triple overtime
00:28:35 even these top
00:28:37 to push their bodies
00:28:46 How do they do it?
00:28:49 Charging down the court,
00:28:51 over 30 quarts
00:28:54 In that same minute,
00:28:56 even the most excited spectator
00:29:02 Hawkins: I think you feel
00:29:05 especially if it's
00:29:07 or if you have
00:29:08 where you're up and down
00:29:10 yeah, you can definitely
00:29:12 and it feels like it's about
00:29:17 Brown: I think
00:29:20 or any one of my peers' body,
00:29:22 and you compare a normal person,
00:29:24 you'd probably just see our
00:29:32 Narrator: Heartbeat
00:29:34 and adjusted
00:29:37 During exercise, when the
00:29:41 messages are sent to speed up
00:29:49 For the hornets, these last
00:29:52 will tax their hearts
00:29:58 Their coach summons
00:30:01 for final instructions.
00:30:17 Final score:
00:30:23 Wesley:
00:30:25 Um, I'm feeling
00:30:27 Feeling a little
00:30:29 My ankles hurt, my feet hurt,
00:30:32 This is the agony of victory.
00:30:39 Sigmon: I'm really impressed
00:30:41 by what NBA players
00:30:43 it's just incredible.
00:30:45 I think they are the
00:30:47 without a doubt.
00:30:49 How they do it night in,
00:30:55 They're running faster,
00:30:57 because I think we're able
00:31:00 It's doing things that we
00:31:03 maybe 10, 20 years ago.
00:31:10 Narrator: How does the human form
00:31:15 We know the bodies of
00:31:19 Are expertly tuned -
00:31:20 his muscles accounting for more
00:31:24 his bones many times stronger
00:31:27 than a steel bar
00:31:29 Together, they're trained
00:31:47 But is it more than fitness that
00:31:51 Scientists and athletes alike
00:31:53 suspect that it is the
00:31:56 that matters most.
00:31:58 Mabloire: I feel that I've been
00:32:01 that everything is just
00:32:04 You know, I'm taking
00:32:08 You know, eventually,
00:32:13 Narrator: This endless
00:32:16 creates much quicker
00:32:20 It is as if extensive training
00:32:26 Gage: A professional basketball
00:32:29 in many ways is a genius
00:32:32 they can run down the court,
00:32:38 and see all the players at the
00:32:42 in ways that people
00:32:52 We're beginning
00:32:54 the implications of the fact
00:32:58 can influence the structure
00:33:01 And very specifically,
00:33:04 can actually increase the number
00:33:15 Coffey: When you have a cell,
00:33:19 this little thing puts out
00:33:23 And as you watch it
00:33:25 it's doing
00:33:28 and it reaches out... gulp...
00:33:30 And as soon as it
00:33:31 it knows what it's touched,
00:33:34 And then it begins
00:33:36 so it can sense the periphery,
00:33:39 your fingertips,
00:33:44 and they all make their way
00:33:47 And the brain is where
00:33:51 are putting all this together.
00:33:53 Says, "Now I can
00:33:57 "Wow! I don't know
00:34:00 I know that
00:34:03 But how does that brain inside
00:34:07 Some strange things
00:34:10 So what the frontier, of course is,
00:34:21 Duffy: Spell the word "man."
00:34:23 M-A-N.
00:34:25 Narrator:
00:34:27 Scott is less than
00:34:30 To give doctors
00:34:32 of how
00:34:35 he undergoes a series of basic
00:34:40 Duffy: Say
00:34:42 They raise good potatoes.
00:34:43 Duffy: "Will you
00:34:44 Will you answer the telephone?
00:34:46 Duffy:
00:34:47 "A glass of milk,
00:34:50 I ordered a ham sandwich...
00:34:53 And...a glass of milk.
00:34:56 Penguin...
00:34:58 Narrator: This knowledge
00:35:00 to perceive change -
00:35:03 as they talk to Scott
00:35:09 And he could
00:35:11 and do it and be over with it
00:35:18 Scott: I need to be conscious
00:35:21 I'm not sure exactly
00:35:24 but that's very intimidating.
00:35:31 Coffey:
00:35:33 your eye has seen
00:35:36 sounds you've heard?
00:35:40 How in the world could you have
00:35:44 and all of those images -
00:35:48 or whatever
00:35:50 and be able to retrieve it
00:35:55 If I say "Saturn's rings,"
00:35:58 in the length of time it took
00:36:02 to retrieve that?
00:36:04 It is so astounding
00:36:08 At how fast the brain works
00:36:16 Narrator: How, and where, the brain
00:36:20 has puzzled scientists
00:36:23 Science is on the trail
00:36:26 and an unexpected answer
00:36:37 London's legendary taxi drivers
00:36:40 are the Olympic athletes
00:36:42 Navigating the intimidating labyrinth
00:36:46 they must create
00:36:54 Kelly: London
00:36:57 It's a massive area,
00:37:00 And it's grown up organically.
00:37:04 So the streets bend,
00:37:06 Osborne: I mean,
00:37:08 Where on one side of the street
00:37:12 And on the other side of the
00:37:15 Lee: London wasn't laid out for
00:37:19 It was laid out for
00:37:22 And it's adapted
00:37:24 So we've had to adapt to it
00:37:29 Narrator: University of London
00:37:33 found ideal subjects
00:37:38 For 150 years,
00:37:41 has had to pass a grueling exam,
00:37:43 known to Londoners
00:37:47 It takes most hopefuls
00:37:50 giving researchers
00:37:53 to look at how the brain
00:37:55 to retain vast amounts
00:37:59 Lee: I don't think there's
00:38:01 where the cab drivers have to
00:38:05 Man: Thanks, mate,
00:38:08 Lee: When somebody gets
00:38:10 they'll say,
00:38:11 It's got to be like that,
00:38:13 where you're going,
00:38:16 So there's a lot of retention -
00:38:18 you've got to retain a lot
00:38:22 Narrator: Here are ordinary
00:38:25 exercising their brains
00:38:29 Scientists suspect that
00:38:32 called the hippocampus - might be
00:38:37 Frackowiac: The hippocampus is a part
00:38:41 It's on the insides of what
00:38:44 which are the parts of the brain
00:38:46 just behind the bone there.
00:38:48 It's two structures,
00:38:50 critical for laying down
00:38:54 Instructor: Now, run me
00:38:57 Student: Leave by Waterloo Bridge,
00:39:00 Narrator: If memory
00:39:02 at the knowledge point school,
00:39:05 surely give this part of
00:39:09 Student: ...Lower Roberts Street...
00:39:10 Student 2: ...right, um,
00:39:12 ...left Shaftsbury Avenue
00:39:14 ...right into
00:39:16 Derek: Dave, give me the name of
00:39:19 With a lady's name.
00:39:20 Dave: Chutney Mary's
00:39:21 Derek: Hereford Road -
00:39:22 Student: veronica's.
00:39:24 Derek: Denise,
00:39:25 contains a restaurant
00:39:28 Would that
00:39:30 Derek: If I then said to you
00:39:34 Zaffaren restaurant?
00:39:38 It's very important,
00:39:40 that you keep them in your mind
00:39:45 That's it. Thank you for
00:39:47 Anything we didn't note,
00:39:50 Thank you very much.
00:39:55 Narrator: After class,
00:39:58 take to the streets.
00:39:59 Since visual processing
00:40:02 than all the other
00:40:05 it is not surprising
00:40:07 is an essential part
00:40:10 You start off
00:40:12 Then you have to learn
00:40:20 With all the routes that you
00:40:23 you couldn't possibly
00:40:26 You have to get out
00:40:28 in the rain, the cold, the snow.
00:40:33 The brain is gradually gathering
00:40:36 more and more
00:40:40 As long as you keep remembering
00:40:43 they will stay in your brain.
00:40:47 Narrator: But how does the brain retain
00:40:51 As the scientists suspected,
00:40:54 may have a physical impact
00:40:58 Their study concluded
00:41:01 was, indeed, larger-than-average
00:41:04 In fact,
00:41:07 were seen in the drivers
00:41:10 Smith: The hippocampus
00:41:13 And what seems to be happening
00:41:16 is that the spatial map
00:41:21 and laying this down caused
00:41:24 and grow,
00:41:26 and that makes part
00:41:31 Kelly: It's almost like
00:41:32 you've somehow, somewhere
00:41:34 you've created enough space
00:41:38 a little bit of software.
00:41:40 Osborne: You've got
00:41:43 On a map in your head.
00:41:45 You've built up a big picture
00:41:49 and you can see the lines
00:41:53 so that you can see
00:41:59 Narrator: This study suggests something
00:42:04 That the adult brain can
00:42:07 according to the requirements
00:42:11 Smith: I think
00:42:13 Because it's shown
00:42:15 that the hippocampus
00:42:20 But what does it mean?
00:42:21 It means that the hippocampus
00:42:24 We say in science it's plastic,
00:42:27 It actually can change shape.
00:42:33 Lee: I definitely feel as if
00:42:35 I've got a larger hippocampus
00:42:37 In fact, it's been said.
00:42:38 I've had people
00:42:40 "I've noticed you've got"
00:42:42 "a larger hippocampus
00:42:44 It's quite interesting really
00:42:46 because we just set out
00:42:48 to learn it for our job.
00:42:50 And now we're being told
00:42:52 that we've exercised
00:42:54 which is enlarged now
00:42:58 it's going to be
00:43:04 Narrator: If human existence
00:43:06 can be described
00:43:09 the implications of the study
00:43:13 Once we wouldn'thave dared to dream
00:43:16 our brains might possess
00:43:19 Now we dream.
00:43:23 to help restore
00:43:25 Alzheimer's patients, and
00:43:39 Mikkaela: I do know that
00:43:42 And I know he's
00:43:44 for a couple of days.
00:43:47 And I know that
00:43:50 how to read and write again,
00:43:53 So I might have
00:43:55 and teach him
00:43:59 And I know that
00:44:02 And my mom is too.
00:44:06 Narrator: It's been a sleepless
00:44:09 so being awake for surgery
00:44:14 Lisa: Right now I just...
00:44:17 where I want to
00:44:19 just 'cause I know
00:44:23 We know and we were told
00:44:25 that he will be banged up
00:44:28 But how long
00:44:31 And how much is it going to be?
00:44:38 I was calm
00:44:42 I tried to follow
00:44:44 and I knew I couldn't
00:44:47 when he got into the pre-op.
00:44:50 It's like I said "goodbye,"
00:44:53 what he would be like
00:45:09 Scott: I'm very scared. There's
00:45:13 It's to protect your brain.
00:45:16 And then all of a sudden
00:45:19 and go into your brain and
00:45:24 You know, the thought that
00:45:28 is gonna... I'm trustingmy head to be dug around in
00:45:32 by this person...
00:45:38 Narrator: Scott must remain absolutely
00:45:42 which could last as long
00:45:45 So his head
00:45:50 The dots from
00:45:53 allow surgeons to align
00:45:56 with his actual brain.
00:46:10 Scott is briefly put to sleep
00:46:12 while his skull
00:46:15 The doctors will soon wake him
00:46:19 Meyer: First thing
00:46:21 is we'll go ahead
00:46:23 confirm the pre-central gyrus
00:46:28 Narrator: Guided by
00:46:30 to see where his eyes cannot,
00:46:32 Dr. Meyer is able to close in
00:46:37 Meyer:
00:46:39 Looks like we're
00:46:43 And anteriorly,
00:46:45 just as you would predict.
00:46:47 So the tumor
00:46:49 from here, all the way
00:46:52 And, of course,
00:46:55 All right, we're gonna start
00:46:59 Narrator: Electrical impulses will
00:47:03 in the specific area
00:47:05 allowing dr. Meyer
00:47:08 without significant loss.
00:47:11 A few millimeters to the left
00:47:14 a few millimeters to the right
00:47:18 Meyer: On...
00:47:20 Scott: Numb...numb...
00:47:21 Soo: Numbness of the arm...
00:47:22 There's a jerk
00:47:25 Meyer:
00:47:27 of his arm, his hand, his
00:47:31 And it's always amazing,
00:47:33 that such a little part of
00:47:37 sort of a miraculous thing.
00:47:45 Narrator: It will be hours
00:47:51 Lisa: I could sit for maybe
00:47:54 but then I would have
00:47:57 I tried to keep myself occupied
00:48:00 I kept looking at my watch
00:48:10 Narrator: As dr. Meyer
00:48:13 dr. Duffy keeps a vigil
00:48:15 to verify that language
00:48:17 Duffy: "Please sit down."
00:48:18 Scott: Please sit down.
00:48:19 "They raise good potatoes."
00:48:21 They raise
00:48:23 "Will you answer the telephone?"
00:48:24 Will you answer the telephone?
00:48:26 Scott: Acorn...whoa, my leg,
00:48:29 Duffy: Your leg?
00:48:31 Scott: ...My leg, my leg...
00:48:34 Duffy: He feels
00:48:37 Meyer: Okay.
00:48:38 Duffy:
00:48:40 Scott: w-A-T-C-H.
00:48:43 Duffy: The word "yellow."
00:48:44 Scott: Y-E-Yell...
00:48:52 Meyer: Is everything okay?
00:48:54 Soo: The right leg is getting
00:48:57 Scott: That one
00:48:59 Meyer: A lot or a little?
00:49:01 Scott: A lot.
00:49:02 Soo: It's about moderate.
00:49:05 Meyer: Okay, so we'll stop
00:49:08 Your speech is just fine,
00:49:13 But we're not gonna resect any
00:49:17 For what it's worth, Scott,
00:49:18 We're getting a very big
00:49:20 Scott: Okay.
00:49:22 Meyer: I think
00:49:24 we're gonna really probably
00:49:27 And I don't think
00:49:29 If I were in your shoes,
00:49:36 Meyer: What patients go through
00:49:39 It's an awful experience.
00:49:44 "Gosh, this was in me
00:49:48 Duffy: Can you see that?
00:49:49 Scott: Yes, I can.
00:49:52 That's the tumor.
00:49:54 Cool. Okay...
00:49:56 Okay? All right.
00:50:11 Meyer: Ah, there you are.
00:50:15 Everything went as well
00:50:18 It looks like
00:50:22 which is better than I thought
00:50:25 In terms of his function, um,
00:50:27 I think it's sort of as
00:50:31 His language is fine.
00:50:33 Lisa: I was very nervous when
00:50:37 Because I was expecting
00:50:43 But as he kept talking, it kept
00:50:48 Got a little bit
00:50:52 Meyer: We would never say
00:50:55 but, I think, in terms
00:50:58 I think what we did today
00:51:00 has given him a good shot
00:51:07 Meyer: Okay? Okay,
00:51:26 Lisa: I was scared to see him,
00:51:30 I walked around the corner slow
00:51:32 because I knew what was ahead,
00:51:37 I expected his face
00:51:40 and on oxygen
00:51:46 but when I saw him, I was, like,
00:51:59 Hey, you...
00:52:01 You made it.
00:52:03 Scott: What I'm feeling right
00:52:10 A little headache?
00:52:11 Yeah.
00:52:12 Lisa: He sounded very good.
00:52:14 He squeezed my hand
00:52:17 for having some weakness
00:52:22 Narrator: Having come
00:52:25 Scott is able to speak and move.
00:52:28 Without awake surgery
00:52:30 and the images that rendered
00:52:33 the result might have been
00:52:38 Lisa: It's good
00:52:41 you know... it's been hard
00:52:45 Lisa: I love you.
00:52:46 I love you, too.
00:52:57 Narrator:
00:52:59 Scott returns to teaching
00:53:02 Someday, his children's
00:53:06 where the leaps of science that
00:53:09 surpassed by new ones
00:53:15 Coffey: Each time a tool
00:53:19 it expands what we can do.
00:53:21 It's like the internet;
00:53:24 So what I have seen happen in my
00:53:30 is the change from a horse and
00:53:35 The computer changes are minor
00:53:38 change in
00:53:43 Narrator:
00:53:45 This understanding
00:53:48 lives that quickly reveal
00:53:51 Born prematurely
00:53:54 Kayla and Kasim Pearson
00:53:57 spend their first weeks
00:53:59 but soon grow
00:54:06 Coffey: Is it magic?
00:54:10 It's like when you hold
00:54:14 You could say, "oh, this is
00:54:17 Wait a minute -
00:54:20 This goes beyond
00:54:24 Where in here does something
00:54:30 A human, when it
00:54:33 makes something that's more than
00:54:37 And that something
00:54:39 is the ability to store
00:54:42 to create, and
00:54:47 This is the mystery
00:54:53 We do not know
00:54:57 Everything we think
00:55:00 to what a human can do
00:55:03 Is proven to be wrong.
00:55:06 And this just means the
00:55:09 can be overcome.
00:55:15 Captioning converted to subtitles
00:55:20 Corrected by m06166.